New York Giants vs 49ers NFL Free Pick, Odds, Preview, Prediction (9/21/23)

NFL

(9/21/23) 8:15PM Eastern.

Spread: Giants +10.5 / 49ers -10.5

ML: Giants +400 / 49ers -550

Over/Under 43.5

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Free Pick: Daniel Jones Over 37.5 Rushing Yards

Daniel Jones is going to have to run frequently if the Giants want a chance at winning this game. With Saquon Barkley out there's really no choice. After giving him big money the Giants were reluctant to run Jones but that gave way last week. After being shut out for 6 straight quarters the Giants unleashed Vanilla Vick. He had 8 carries for 58 yards as he led the Giants to 31 2nd half points. That's after having just 1 carry in the first half.