Kansas City Chiefs vs New York Giants NFL Free Pick, Odds, Preview, Prediction (9/21/25)

NFL

8:20 PM EST.

Spread: KC -6 / NYG +6.

ML: KC -300 / NYG +240.

Over/Under: 45.

Free Pick: Chiefs -6.

The 0-2 New York Giants host the 0-2 Kansas City Chiefs with both teams battling to get their first win on Sunday Night Football. The Giants have been their usual selves with recent confidence building after the offense put up 37 against the Cowboys last week with Russel Wilson at the helm. The same can't be said for the Chiefs, who are having a disappointing start to the season, to say the least, following their loss in the Super Bowl. While both teams are winless, their losses have been very different. The Giants looked hopeless in Week 1 against a good Commanders team and then lost in a shootout against a bad Cowboys team. As for the Chiefs, they lost back-to-back one-possession games that could've gone the other way against two very good teams in the Eagles and Chargers. Expect them to bounce back at MetLife and for a resurgence in their running game against a Giants defense that has allowed 5.9 YPC with two LBs on the IR and another two on the injury report.