Kansas City Chiefs vs Jacksonville Jaguars NFL Free Pick, Odds, Preview, Prediction (10/6/25)

NFL

8:15 PM EST.

Spread: KC -3.5 / JAC +3.5.

ML: KC -200 / JAC +165.

Over/Under: 45.5.

Free Pick: Jaguars +3.5.

The Chiefs are road favorites tonight, going up against a good Jaguars team. The Jaguars have been good all around and have surprised many with how much they have improved. Trevor Lawrence has been given clean pockets with his O-line only allowing 3 sacks, and their rushing is the 4th best in the league. Defensively, they've been one of the best, ranking 1st in takeaways, 3rd in run defense, and the 4th in fewest points allowed. The Chiefs' 22nd-ranked run defense will be their cyrptoknite in tonight's matchup. The Jaguars' rushing attack will see little resistance, and that has been their ticket to winning so far this year. Expect a close game in Jacksonville, but don't be surprised if the Jaguars continue their winning ways.